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Hypertension And Tricuspid Regurgitation Is Important Worse Predictor Of Long-term Outcome In Aortic Valve Replacement For Aortic Stenosis
Sung-Ji Park1, Dong Seop Jeong1, Sang-Chol Lee1, Seung Woo Park1, Dong-Ju Choi2, Pyo Won Park1.
1Samsung Medical Center, Seoul, Korea, Republic of, 2Seoul National University Bundang Hospital, Seongnam, Korea, Republic of.

OBJECTIVE: After the establishment of aortic valve replacement procedure for aortic stenosis, there are heterogeneous studies and varying reports on outcome.
METHODS: Between 1995 and 2009, 383 patients underwent AVR for severe AS (female 128, 63.2±13.9 yrs). Of these patients, 343 patients have normal LV systolic function (EF >40%) preoperatively. Primary end-point was cardiac-related mortality. Mean follow-up of 53.2±43.5 month.
RESULTS: Cardiac-related deaths occurred in 11 patients. Multivariate analysis identified two significant variables that were predictive of cardiac-related mortality: Hypertension (HR=3.225, 95% CI=1.002-10.378, p=0.045), and TR (≥mild) (HR=3.09, 95% CI=1.017-9.392, p=0.047).
CONCLUSIONS: The presences of hypertension and TR have an additive adverse effect on cardiac-related mortality in AVR for AS.

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