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New York City Conference

Back to 2014 Annual Meeting Abstracts


Learning Curve: Comparison of Early experience in Cohort B during Partner trial to Recent Results in Post Approval Era
elizabeth K. walsh, Nimesh Desai, Wilson Szeto, Prashanth Vallabhajosyula, Saif Anwaruddin, Jay Giri, Howard Herrmann, Joseph Bavaria.
University of Pennsylvania, Philadelphia, PA, USA.

OBJECTIVE: By analyzing your Transcatheter Aortic Valve (TAVR) program a site will understand the impact of patient selection, procedure techniques and post-operative care of the TAVR patient. The purpose of the study was to understand effect of the learning curve on our TAVR program.
METHODS: We looked at 42 patients from Partner l cohort B (P1B) implanted 11/2007 - 7/2009, 102 patients from Partner llB (PllB) implanted 7/2011 - 11/2013 and 186 patients with commercial Sapien implanted 2/2012 - 10/2013. A comparison of patient's age, Society of Thoracic Surgery risk score (STS) and gender was prepared. A Kaplan-Meier (KM) survival curve was performed.
RESULTS: There was no significant difference of ages in all 3 cohorts with P value =0.562%. There was a significantly higher incidence of female patients in the commercial cohort with a P value 0.002%. The P1B cohort had a significantly higher occurrence in the commercial population with a p valve=0.29%. The KM demonstrated a significantly higher mortality in P1B cohort compared to P2B or commercial (fig 1.).
CONCLUSIONS: Programs will experience a learning curve. Shortening the learning curve requires continued education on patient selection, technical experience and care of the TAVR patient. As the technology continues to evolve and devices improve so will the demand for TAVR. It is crucial that educational needs are met as your Heart Team grows.


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